Bonnie Ky, MD, and Marcely Gimenes Bonatto, MD, discuss the study design, findings, future research questions and the potential clinical impact of the use of sacubitril/valsartan for the prevention of cardiotoxicity in high-risk patients undergoing anthracycline chemotherapy.
Nicholas Wilcox, MD, MHS, Darryl Leong, MBBS, MPH, M.Biostat, PhD discuss
Emile Daoud, MD, Associate Editor of JACC: Clinical Electrophysiology discusses a recently published original research paper on the Safety and Feasibility of Pulsed Field Ablation in Patients with Mechanical Prosthetic Valves
Mirza Umair Khalid, MD, social media editor of JACC: Cardiovascular Interventions, and Thomas J. Stocker, MD, discuss a recently published original research paper reporting the long-term outcomes after mitral transcatheter edge-to-edge repair for secondary mitral regurgitation.
Dr. Danyan Xu is a chief physician, professor, and the director of the Cardiac Rehabilitation Unit of the Department of Cardiovascular Medicine of the Second Xiangya Hospital, Central South University. She shares insights into cardiac rehabilitation. Moderated by Dr. Zhangling Chen.
What is the current state of evidence behind the use of traditional Chinese medicine in the treatment of cardiovascular disease? Dr. Iokfai Cheang sheds light on this topic through both a clinical and research lens as we discuss the Luobing theory of traditional Chinese medicine.
Novi Yanti Sari, MD, social media editor of JACC: Heart Failure, discusses a recently published original research paper that explored new ways to manage hyperkalemia in patients with HFrEF.
Nikhil Narang, MD, social media editor of JACC: Heart Failure, discusses a recently published original research paper on the clinical trajectory of patients with advanced ambulatory heart failure in the REVIVAL trial.
JACC Heart Failure Associate Editor Sean Pinney, MD, discusses a recently published original research paper that explores the results of a randomized controlled trial to test whether evolocumab reduces the burden of cardiac allograft vasculopathy.
In this episode of the JACC: Asia podcast, Editor-in-Chief Jian'an Wang provides a concise summary of the November 2024 issue, featuring five impactful studies on cardiovascular and metabolic health in Asian populations. Highlights include research on patient mismatch after aortic valve replacement, outcomes of mitral valve repair, and genetic links between lipid levels and type 2 diabetes risk, underscoring the importance of personalized healthcare approaches for Asian patients.
In this podcast, Editor-in-Chief Jian'an Wang discusses the ongoing debate over patient-prosthesis mismatch (PPM) following transcatheter aortic valve replacement (TAVR), highlighting conflicting findings between Western and Asian cohorts. Recent data from the updated Ocean TAVR registry suggests that severe PPM is an independent risk factor for long-term mortality and rehospitalization, underscoring the need for personalized device selection to improve outcomes, particularly in patients with smaller annuli and larger body surface areas.
In this episode of the JACC: Asia podcast, Editor-in-Chief Jian'an Wang examines a study which explores the genetic links between lipid levels and type 2 diabetes risk in the Chinese population, using data from the Quinson community cohort. The findings suggest that lower genetic risk scores for LDL-C and triglycerides are associated with a higher risk of diabetes, highlighting the need for personalized lipid management strategies, especially in light of the potential risks of long-term APOC inhibitor use.
In this episode of the JACC: Asia podcast, Editor-in-Chief Jian'an Wang examines a large-scale study revealing that early ablation for atrial fibrillation significantly reduces the risk of arrhythmia recurrence in heart failure patients, compared to delayed ablation. While timing of the procedure didn't affect mortality or heart failure hospitalization rates, these findings emphasize the importance of timely intervention for better long-term outcomes in this patient group.
In this episode of the JACC: Asia podcast, Editor-in-Chief Jian'an Wang examines the link between pre-pregnancy cardiometabolic factors, such as BMI and hypertension, and the risk of gestational diabetes among Asian populations in the United States. The findings highlight the elevated prevalence of gestational diabetes in these groups and stress the need for early screening and intervention to improve outcomes for high-risk patients.
In this episode of the JACC: Asia podcast, Editor-in-Chief Jian'an Wang examines the EXPAND G4 study and evaluates the one-year outcomes of the first-generation Edge-to-Edge mitral valve repair device in 95 Japanese patients, demonstrating a 100% implantation success rate and significant improvements in mitral regurgitation severity and functional capacity. These promising results underscore the potential of this device to deliver excellent clinical outcomes for Asian patients with mitral valve disease.
In this episode of the JACC: Asia podcast, Professor Hao-Min Cheng discusses a study on the association between pre-pregnancy cardiometabolic factors and the risk of gestational diabetes among Asian populations in the U.S., revealing that higher BMI and hypertension significantly increase the risk. The study also highlights that Asian Americans, despite having lower rates of obesity and hypertension, face a notably higher prevalence of gestational diabetes, emphasizing the need for further research on body fat distribution and early glucose screening to better manage this risk.
In this episode of the JACC: Asia podcast, Cheol Hyun Lee explores the prognostic impact of patient-prosthesis mismatch (PPM) following transcatheter aortic valve replacement (TAVR) in Asian patients, who tend to have smaller annular sizes compared to Western populations. The study highlights that while severe PPM occurs in only 1.3% of patients, it is significantly linked to a higher risk of heart failure hospitalization, underscoring the need for personalized treatment approaches in Asia to reduce the risk of severe PPM.