In this episode of the JACC: Asia podcast, Editor-in-Chief Jian'an Wang examines a study which explores the genetic links between lipid levels and type 2 diabetes risk in the Chinese population, using data from the Quinson community cohort. The findings suggest that lower genetic risk scores for LDL-C and triglycerides are associated with a higher risk of diabetes, highlighting the need for personalized lipid management strategies, especially in light of the potential risks of long-term APOC inhibitor use.